As a dietary supplement, take one (1) softgel in the morning and one (1) softgel in the evening with meals.
Gelatin (beef sourced), glycerin, yellow beeswax, lecithin (soy), soybean oil, water and caramel (colors).Contains Soy
How was the Focus Select® formulation developed?
Focus Select is based on peer-reviewed findings and analysis of the Age-Related Eye Disease Studies (AREDS) conducted by the National Eye Institute (NEI), a division of the National Institute of Health.
In 1992, the National Eye Institute launched the large-scale AREDS study to investigate the impact of supplementation on patients with AMD. The 2001 findings demonstrated that high doses of antioxidant vitamins and minerals slowed the progression of AMD in people with intermediate AMD and those with Advanced AMD in one eye by an average of 25% over a five-year period.
Original AREDS formulation:
- 500 mg of vitamin C
- 400 international units of vitamin E
- 15 mg beta-carotene
- 80 mg zinc oxide
- 2 mg copper as cupric oxide
AREDS2 was a follow-up study conducted to in effort to improve upon the original formula. The original AREDS contained beta-carotene, an antioxidant found to be associated with an increased risk of lung cancer in smokers in two large trials funded by the National Cancer Institute. The original formula also contained 80 mg of zinc, a level considered too high by some nutritionists and which is associated with side effects in some patients.
Modifications tested in AREDS2:
- 10 mg of lutein and 2 mg zeaxanthin
- 1000 mg omega-3 fatty acids
- Removing beta-carotene
- Reducing zinc levels to 25 mg
AREDS2 findings impacting supplementation:
- Replacing the antioxidant beta-carotene with lutein and zeaxanthin in the AREDS2 trial resulted in a slight reduction in risk of advanced AMD compared to the original AREDS with beta-carotene
- Adding Omega-3 fatty acids did not improve the risk of advanced AMD overall
- Lowered zinc levels were found to be as effective as the original formulation
Who should take Focus Select®?
Focus Select should only be considered by those at risk for developing advanced AMD. Prior to taking the levels of vitamins and minerals found in our formula, patients should speak with their doctor about the risk of developing advanced AMD and whether taking Focus Select is right for them.
Will taking Focus Select® cure AMD?
No. There are currently no treatments for dry AMD. While the AREDs formulations may slow the progression of dry AMD in people with moderate levels of disease by 25%, no supplement has demonstrated the ability to improve or restore vision.
Can patients take a daily multivitamin if they are taking Focus Select®?
Yes. Most people in the AREDS studies also took multivitamins. However, you should first consult with your primary care doctor and receive their approval to take a multivitamin in conjunction with Focus Select.
Can patients take a daily multivitamin instead of Focus Select®?
No. While a multivitamin has a broad spectrum of vitamins and minerals, it does not contain the high levels of specific antioxidants proven to be effective in the AREDS2 study.
Should patients consider changing to Focus Select® if they are on an original AREDS formula?
Yes. Replacing beta-carotene with lutein/zeaxanthin is safer for smokers and showed a lower risk of progression (18%) of AMD in AREDS subjects compared with those in the AREDS2 trial. Additionally, the 25 mg dose of zinc in lieu of 80 mg may prevent side common side effects associated with zinc.